CJC-1295/Ipamorelin Blend (No DAC/5mg/5mg)

The CJC-1295/Ipamorelin Blend pairs two complementary growth hormone (GH) secretagogues in a single vial: 5 mg of CJC-1295 without DAC (also known as Modified GRF 1-29), a short-acting analog of growth hormone-releasing hormone (GHRH), and 5 mg of Ipamorelin, a highly selective growth hormone-releasing peptide (GHRP) and ghrelin-receptor mimetic. This GHRH-plus-GHRP combination is one of the most widely referenced secretagogue blends in laboratory research and is supplied as a lyophilized powder for research use only.

Scientific Foundation and Study Background

Each component of the blend acts on a distinct pituitary pathway. CJC-1295 (no DAC) binds the GHRH receptor on somatotroph cells to increase the amplitude of GH pulses, while Ipamorelin activates the ghrelin / growth hormone secretagogue receptor (GHS-R1a) to initiate a GH pulse and reduce somatostatin tone. Human pharmacokinetic characterization of ipamorelin was first published by Gobburu and colleagues in Pharmaceutical Research (1999), and GHRH-analog pharmacology has been documented across multiple endocrine studies. In research models the two mechanisms are reported to act synergistically.

• GHRH analogs and GHRP/ghrelin mimetics act on separate receptors (GHRHR and GHS-R1a), and combined administration produces greater GH release than either class alone in research models.
• Ipamorelin showed dose-proportional pharmacokinetics with a terminal half-life of about 2 hours and a single discrete GH pulse peaking near 0.67 h in healthy human volunteers (Gobburu et al., Pharmaceutical Research, 1999).
• Ipamorelin is reported to be highly selective for GH release, with negligible stimulation of ACTH, cortisol, prolactin, FSH, LH or TSH at studied doses, distinguishing it from earlier GHRPs.

Biochemical Properties and Stability

The blend contains two chemically distinct peptides. CJC-1295 (no DAC) is a 29-residue GHRH(1-29) analog carrying stabilizing substitutions, including a D-Ala at position 2 that confers resistance to DPP-IV cleavage; because it lacks the Drug Affinity Complex (DAC) albumin-binding moiety, it remains short-acting. Ipamorelin is a synthetic pentapeptide built around an Aib residue and D-amino acids for protease stability. Both are supplied lyophilized and are most stable when stored at -20 degrees C, protected from light and moisture; reconstituted solutions are handled cold for laboratory work.

• CJC-1295 (no DAC / Mod GRF 1-29) sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
• Ipamorelin sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
• Molecular formula: C152H252N44O42 (CJC-1295 no DAC); C38H49N9O5 (Ipamorelin)
• Molar mass: ~3367.9 g/mol (CJC-1295 no DAC); ~711.9 g/mol (Ipamorelin)
• CAS: 863288-34-0 (CJC-1295 no DAC / Mod GRF 1-29); 170851-70-4 (Ipamorelin)
• Systemic half-life: ~30 minutes (CJC-1295 no DAC, short-acting GHRH analog); ~2 hours (Ipamorelin, human volunteers)
• Form: lyophilized white powder, at least 99% purity (HPLC)

Buy CJC-1295/Ipamorelin Blend (No DAC/5mg/5mg) at Bergdorf Bioscience

Bergdorf Bioscience supplies the CJC-1295/Ipamorelin blend as a 5 mg + 5 mg dual-peptide vial of lyophilized powder, manufactured to a verified purity of at least 99% by HPLC and accompanied by third-party analytical testing. Each batch is screened for identity and purity so that research outcomes remain reproducible.

• Composition: 5 mg CJC-1295 (no DAC / Mod GRF 1-29) plus 5 mg Ipamorelin per vial
• Purity: at least 99% confirmed by HPLC, with a third-party certificate of analysis
• Reconstitution: with bacteriostatic or sterile water for laboratory handling only (research context)
• Storage: lyophilized at -20 degrees C; keep reconstituted material cold and protected from light
• Intended use: in-vitro and non-human laboratory research only, not for human or veterinary use

This product is sold strictly as a research chemical. It is not a medicine, supplement, or cosmetic, and no statement here should be interpreted as medical, therapeutic, or dosing guidance for humans or animals.

Worldwide Shipping

Bergdorf Bioscience ships the CJC-1295/Ipamorelin blend worldwide with discreet, temperature-conscious packaging to protect peptide integrity in transit. Orders are processed promptly and dispatched with tracking so research laboratories receive their material reliably.