

Arvuta iga peptiidi jaoks täpsed lahuse mahud, insuliiniühikud ja annuste arv viaali kohta.
Viaal, vesi ja annus on teada
Ühikud mõõdavad mahtu, mitte toimeainet. 8 IU = 0,08 ml. Mitu mg selles on, sõltub segust. Kalkulaator on selle sinu eest välja arvutanud.
Peaaegu kõik insuliinisüstlad on U-100. Vali U-40 ainult siis, kui süstal on tähistatud U-40.
Lingitud allikad viivad PubMedisse ja avanevad uuel vahelehel.
Teadusprofiil
Ipamorelin peptiidileksikonis: mehhanism, tõendus ja allikad
Kaasas olev tööriist
Vaata, kui kaua Ipamorelin organismis püsib
Ipamorelin is a synthetic pentapeptide growth hormone-releasing peptide (GHRP) widely regarded as the most selective GH secretagogue available in research. Unlike older GHRPs, it stimulates growth hormone release without significantly raising cortisol or prolactin. This guide covers everything you need: mechanism of action, dosage calculation, reconstitution protocol, storage, safety profile, and how to effectively combine Ipamorelin with CJC-1295 No DAC and other peptides.
Medical Disclaimer: The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Peptides are not approved drugs for human use. Always consult a qualified healthcare provider before using peptides.
Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. Originally developed at Novo Nordisk in the 1990s, it underwent Phase II clinical trials for postoperative ileus and growth hormone deficiency. Though it never reached pharmaceutical approval, Ipamorelin became one of the most extensively studied GHRPs in biomedical research and remains a benchmark compound in its class.
Structurally, Ipamorelin belongs to the family of ghrelin mimetics. It binds to the growth hormone secretagogue receptor type 1a (GHS-R1a), expressed in both the anterior pituitary and the hypothalamus. What distinguishes Ipamorelin from earlier compounds such as GHRP-2 and GHRP-6 is its receptor selectivity: at research doses, it produces robust GH release without meaningful stimulation of cortisol, ACTH, or prolactin — a profile that makes it uniquely well-tolerated and suitable for combination protocols.
Ipamorelin activates GHS-R1a receptors on somatotroph cells in the anterior pituitary. This triggers intracellular calcium mobilization via the phospholipase C/IP₃ pathway, stimulating the pulsatile secretion of growth hormone. Concurrently, Ipamorelin suppresses somatostatin — the hypothalamic inhibitor of GH release — amplifying the net GH pulse.
The resulting GH elevation drives hepatic IGF-1 (Insulin-like Growth Factor 1) production, which mediates the downstream anabolic and lipolytic effects associated with GH axis activation. Potential effects include:
The defining feature of Ipamorelin is its selectivity for somatotroph GH release over other neuroendocrine axes. GHRP-2 produces significant cortisol and prolactin elevations alongside GH — complicating protocols that require stress-hormone neutrality. GHRP-6 powerfully stimulates appetite via central ghrelin receptors. Ipamorelin shows neither effect at clinically relevant doses. This selectivity is not incidental but results from its specific structural affinity for the GHS-R1a subtype expressed in the pituitary, without meaningful cross-reactivity at other receptor populations. For researchers designing multi-peptide protocols, this clean pharmacological profile simplifies interpretation of outcomes and reduces confounding variables.
Accurate dosage calculation is critical for both efficacy and safety. Standard dosing parameters for Ipamorelin are:
Ipamorelin does not require a titration phase. The standard dose can be used from the first injection, though some practitioners prefer starting at the lower end of the range (200 mcg) for the first week to assess individual response.
The standard BergdorfBio Ipamorelin vial contains 5 mg of lyophilized peptide. Adding 2 ml of bacteriostatic water (BAC water) yields a concentration of:
5 mg ÷ 2 ml = 2.5 mg/ml = 2,500 mcg/ml
Using a U100 insulin syringe (0.3 ml capacity, 100 units = 1 ml):
At 200 mcg three times daily (600 mcg/day), one 5 mg vial lasts approximately 8 days. At 200 mcg twice daily (400 mcg/day), the same vial lasts approximately 12 days.
With 2 mg peptide and 2 ml BAC water, the concentration is 1 mg/ml (1,000 mcg/ml):
For instant volume calculations based on your exact vial size, reconstitution volume, and target dose, use the BergdorfBio Peptide Calculator. Enter your parameters to get the precise draw volume in both milliliters and insulin units.
Ipamorelin is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before injection. You will need:
Use only bacteriostatic water or water for injection (WFI). Do not use tap water, commercially available distilled water, or saline solutions not specifically intended for injection use. Incorrect solvents can degrade the peptide or introduce contaminants.
Ipamorelin has one of the most favorable tolerability profiles among peptide GH secretagogues. Clinical studies and research protocols consistently report low rates of adverse events at standard doses.
Unlike GHRP-2, Ipamorelin does not produce clinically meaningful cortisol or prolactin elevation at research doses. Unlike GHRP-6, it does not induce significant appetite stimulation via central ghrelin receptor activation. This selectivity is a core safety advantage that distinguishes Ipamorelin from earlier-generation GHRPs.
Stop immediately and consult a physician if you experience persistent swelling, severe or worsening headache, visual disturbances, joint pain beyond normal soreness, or any other unusual or concerning symptoms.
The combination of Ipamorelin with CJC-1295 No DAC is the most studied and most widely used growth hormone peptide protocol. The rationale is mechanistic synergy: CJC-1295 No DAC activates the GHRH receptor on pituitary somatotrophs, while Ipamorelin simultaneously activates GHS-R1a. These two pathways converge to produce a substantially larger GH pulse than either peptide achieves alone — an effect consistent across preclinical models and observational research.
The pairing is particularly well-suited because Ipamorelin's selectivity (no cortisol, no prolactin elevation) maintains a clean hormonal backdrop that complements CJC-1295's GHRH-mediated stimulation. The two peptides are chemically compatible and can be drawn into the same insulin syringe for a single injection.
For research focused on fat metabolism and body recomposition, AOD-9604 (a modified fragment of GH, residues 176–191) can be added. AOD-9604 acts directly on adipocytes to stimulate lipolysis and inhibit lipogenesis without activating the full GH axis or elevating IGF-1. When combined with Ipamorelin, the protocol covers both the central GH pulsatility (via GHS-R1a activation) and the peripheral lipolytic pathway (via the AOD-9604 fragment).
This three-peptide protocol combines GHRH receptor stimulation (CJC-1295 No DAC), ghrelin receptor activation (Ipamorelin), and direct lipolysis (AOD-9604). It addresses GH pulsatility, IGF-1 elevation, and fat-cell metabolism through independent but complementary mechanisms. Experienced researchers may find this stack produces synergistic outcomes for body composition, recovery, and sleep quality — but it demands careful protocol design and physician-supervised monitoring.
Ipamorelin is available at BergdorfBio in 2 mg and 5 mg research-grade vials with verified purity and identity testing.
All three bind to GHS-R1a but differ critically in receptor selectivity. GHRP-2 produces significant elevations in both cortisol and prolactin alongside GH — an undesirable profile for most research applications. GHRP-6 is a potent appetite stimulant via central ghrelin receptor activation in the hypothalamus. Ipamorelin does neither at research doses. Its selectivity for pituitary somatotrophs over other GHS-R1a-expressing tissues makes it the cleanest available GHRP for combination protocols.
Yes. Both peptides are chemically compatible. Draw the first peptide into the insulin syringe, then add the second. Inject subcutaneously immediately after mixing. Do not store pre-mixed peptide solutions — mix fresh for each injection.
The two most effective windows are: (1) immediately upon waking, before any food intake or carbohydrate consumption; and (2) 30–60 minutes before sleep. Both windows align with naturally low insulin levels — insulin strongly suppresses pituitary GH responsiveness, so minimizing post-meal insulin is critical for maximizing GH pulse amplitude. Avoid injecting within 2 hours of a carbohydrate-heavy meal.
Improved sleep quality and faster exercise recovery are typically the earliest reported effects, often within 2–3 weeks. Measurable changes in body composition — increased muscle definition, reduced subcutaneous fat — generally emerge after 8–12 weeks. This timeline reflects the gradual accumulation and sustained elevation of IGF-1 required for tissue-level remodeling. Baseline and follow-up IGF-1 blood tests at 4–6 weeks provide objective confirmation of response.
No. Ipamorelin works by amplifying the pituitary's own capacity to secrete GH in response to physiological stimuli — it does not introduce exogenous GH. Unlike synthetic GH administration, there is no established mechanism for Ipamorelin to suppress the hypothalamic-pituitary axis. That said, prolonged continuous use may theoretically cause some degree of GHS-R1a desensitization. Standard protocol practice of cycling 8–12 weeks on with 4-week breaks is considered a reasonable precaution.
Strongly recommended. Establishing baseline IGF-1 levels allows monitoring of treatment response and ensures IGF-1 does not exceed the upper limit of normal — chronically elevated IGF-1 carries health risks including association with certain malignancies. A physician can also screen for contraindications (pituitary disorders, diabetes, active cancer) that would make Ipamorelin use inappropriate.
Ipamorelin is administered subcutaneously (SC) — injected into the subcutaneous fat layer just beneath the skin. Common injection sites include the lateral abdomen (flanks, away from the navel), the anterior thigh, and the triceps region. Insert the syringe at a 45°–90° angle depending on subcutaneous fat depth. Rotate sites with each injection to prevent local tissue reactions.
BergdorfBio offers Ipamorelin in verified research quality in both 2 mg and 5 mg vials. Each batch is tested for identity and purity. Visit the product page for current availability and pricing.
Legal status varies by jurisdiction. In most countries Ipamorelin is not approved as a pharmaceutical drug for human therapeutic use and is classified as a research chemical. It is prohibited in competitive sports under WADA regulations. Verify the applicable regulations in your country before purchasing or using this compound.
Disclaimer: This content is for informational and research purposes only. Ipamorelin is not an approved drug for human therapeutic use. The applications described have not been evaluated or approved by the FDA, EMA, or any other regulatory authority. Do not use peptides without the supervision of a qualified medical professional.
Pulbrist valmis süstlani viie sammuga. Ülalolev kalkulaator annab kogused automaatselt.
Lase viaalil ja veel jõuda toatemperatuurini. Pühi mõlemad kummikorgid alkoholilapiga.
Tõmba kalkulaatori soovitatud BAC-vee kogus suurema süstlaga.
Lase veel voolata mööda peptiidiviaali siseseina, ära pihusta seda otse pulbrile.
Keeruta viaali õrnalt, ära raputa. Pulber lahustub selgeks 1-2 minuti jooksul.
Tõmba insuliinisüstlaga täpselt arvutatud kriipsuni. Valmis.
Tavalised algväärtused orienteerumiseks. Iga rida avab selle peptiidi kalkulaatori.
| Peptiid | Kategooria | Tavaline annus | Viaalisuurused | BAC (algus) | Saadaval | Arvuta |
|---|---|---|---|---|---|---|
| VIP | Neuropeptiidide uurimine | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Cagrilintide | Amüliini analoog | - | 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHK-Cu | Vaskepeptiid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Ainult kalkulaator | Arvuta |
| AHK-Cu | Vaskepeptiid | - | 100 mg | 5 ml | Ainult kalkulaator | Arvuta |
| BPC-157 | Kudede taastamine | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| CJC-1295 (ilma DAC-ta) | GHRH analoog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| AOD-9604 | Rasvade ainevahetus | 250-500 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| MOTS-c | Mitokondriaalne | 5-10 mg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Selank | Anksiolüütiline | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Ainult kalkulaator | Arvuta |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Ainult kalkulaator | Arvuta |
| Melanotan II | Melanokortiin | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Melanotan I | Melanokortiin | - | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Sermorelin | GHRH analoog | 50-300 mcg | 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Tesamorelin | GHRH analoog | 1-2 mg | 10 / 20 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Thymosin Alpha-1 | Tüümusepetiid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
| Epithalon | Pikaajalisus | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Ainult kalkulaator | Arvuta |
| KPV | Immuunsüsteem / barjäär | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH Fragment 176-191 | Metaboolne fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Semax | Kognitiivne | 100-1000 mcg | 10 / 30 mg | 2 ml | Ainult kalkulaator | Arvuta |
| N-Acetyl Semax | Kognitiivne | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| DSIP | Uni | 50-500 mcg | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| 5-Amino-1MQ | Metaboolne | 2,5-10 mg | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Pinealon | Uurimispeptiid | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Survodutide | GLP-1/glükagoon | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH 191AA | Kasvuhormoon | 1-5 mg | 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
| NAD+ | Pikaajalisus / kofaktor | 100-500 mg | 1000 mg | 10 ml | Ainult kalkulaator | Arvuta |
Väärtused on mõeldud orienteerumiseks uurimiskontekstis ega asenda professionaalset nõuannet.
Kontsentratsiooni ja süstemahu õige arvutamine tundub tühine, kuid on kõige sagedasem veaallikas. Isegi 10 % suurune arvutusviga lahuse valmistamisel tähendab, et saad kas liiga vähe toimeainet või manustad kogemata üleannuse.
Lüofiliseeritud peptiide müüakse milligrammides ja need lahustatakse bakteriostaatilises vees (BAC-vesi). Peptiidi ja vee suhe määrab kontsentratsiooni ja sellest tuleneb, mitu ühikut insuliinisüstlale tõmbad. Insuliinisüstlaid gradueeritakse ühikutes, mitte milligrammides. Kalkulaator teeb selle ümberarvutuse ära, sealhulgas mõistlikkuse kontrolli kõige ohtlikuma vea vastu: mg ja mcg segiajamine.
Milligramm (mg) on ühik, milles lüofiliseeritud peptiide müüakse, näiteks „5 mg BPC-157". Mikrogramm (mcg) mõõdab üksikannust, näiteks „250 mcg süsti kohta". 1 mg = 1000 mcg. Kalkulaator teeb ümberarvutuse automaatselt ja hoiatab, kui sisestus tundub segiaetud olevat.
U-100 tähendab, et süstal on kalibreeritud 100 ühikule milliliitri kohta. 100 IU = 1 ml, seega 10 IU = 0,10 ml, sõltumata sellest, mis süstlas on. IU arvutus põhineb täpselt sellel seosel.
Palju peptiidi ja vähe vett teeb lahuse väga kontsentreerituks, mistõttu maht annuse kohta on tilluke ja raskesti loetav. Kasuta segamise abivahendit: see leiab veekoguse, millega tekib puhas ja hästi loetav kriips.
Külmkapis 2-8 °C juures tavaliselt 21-30 päeva. Märgista viaalile lahuse valmistamise kuupäev. Hägused lahused või osakesed ei kõlba.
Segud sisaldavad ühes viaalis mitut toimeainet. Vali peptiidiks lihtsalt segu: kalkulaator näitab lisaks, kui palju igat komponenti sinu süstis on. Mitme eraldi viaali kombinatsiooni jaoks kasuta Stack Builderit.
Ei. Sinu viimased seaded salvestatakse lokaalselt brauserisse ja taastatakse järgmisel külastusel. Arvutusi saad ka ajaloost tagasi kutsuda, protokollina salvestada või lingina jagada.
Vali peptiid, et avada selle kalkulaatorileht eeltäidetud väärtustega.
Arvuta iga peptiidi jaoks täpsed lahuse mahud, insuliiniühikud ja annuste arv viaali kohta.
Viaal, vesi ja annus on teada
Ühikud mõõdavad mahtu, mitte toimeainet. 8 IU = 0,08 ml. Mitu mg selles on, sõltub segust. Kalkulaator on selle sinu eest välja arvutanud.
Peaaegu kõik insuliinisüstlad on U-100. Vali U-40 ainult siis, kui süstal on tähistatud U-40.
Lingitud allikad viivad PubMedisse ja avanevad uuel vahelehel.
Teadusprofiil
Ipamorelin peptiidileksikonis: mehhanism, tõendus ja allikad
Kaasas olev tööriist
Vaata, kui kaua Ipamorelin organismis püsib
Ipamorelin is a synthetic pentapeptide growth hormone-releasing peptide (GHRP) widely regarded as the most selective GH secretagogue available in research. Unlike older GHRPs, it stimulates growth hormone release without significantly raising cortisol or prolactin. This guide covers everything you need: mechanism of action, dosage calculation, reconstitution protocol, storage, safety profile, and how to effectively combine Ipamorelin with CJC-1295 No DAC and other peptides.
Medical Disclaimer: The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Peptides are not approved drugs for human use. Always consult a qualified healthcare provider before using peptides.
Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. Originally developed at Novo Nordisk in the 1990s, it underwent Phase II clinical trials for postoperative ileus and growth hormone deficiency. Though it never reached pharmaceutical approval, Ipamorelin became one of the most extensively studied GHRPs in biomedical research and remains a benchmark compound in its class.
Structurally, Ipamorelin belongs to the family of ghrelin mimetics. It binds to the growth hormone secretagogue receptor type 1a (GHS-R1a), expressed in both the anterior pituitary and the hypothalamus. What distinguishes Ipamorelin from earlier compounds such as GHRP-2 and GHRP-6 is its receptor selectivity: at research doses, it produces robust GH release without meaningful stimulation of cortisol, ACTH, or prolactin — a profile that makes it uniquely well-tolerated and suitable for combination protocols.
Ipamorelin activates GHS-R1a receptors on somatotroph cells in the anterior pituitary. This triggers intracellular calcium mobilization via the phospholipase C/IP₃ pathway, stimulating the pulsatile secretion of growth hormone. Concurrently, Ipamorelin suppresses somatostatin — the hypothalamic inhibitor of GH release — amplifying the net GH pulse.
The resulting GH elevation drives hepatic IGF-1 (Insulin-like Growth Factor 1) production, which mediates the downstream anabolic and lipolytic effects associated with GH axis activation. Potential effects include:
The defining feature of Ipamorelin is its selectivity for somatotroph GH release over other neuroendocrine axes. GHRP-2 produces significant cortisol and prolactin elevations alongside GH — complicating protocols that require stress-hormone neutrality. GHRP-6 powerfully stimulates appetite via central ghrelin receptors. Ipamorelin shows neither effect at clinically relevant doses. This selectivity is not incidental but results from its specific structural affinity for the GHS-R1a subtype expressed in the pituitary, without meaningful cross-reactivity at other receptor populations. For researchers designing multi-peptide protocols, this clean pharmacological profile simplifies interpretation of outcomes and reduces confounding variables.
Accurate dosage calculation is critical for both efficacy and safety. Standard dosing parameters for Ipamorelin are:
Ipamorelin does not require a titration phase. The standard dose can be used from the first injection, though some practitioners prefer starting at the lower end of the range (200 mcg) for the first week to assess individual response.
The standard BergdorfBio Ipamorelin vial contains 5 mg of lyophilized peptide. Adding 2 ml of bacteriostatic water (BAC water) yields a concentration of:
5 mg ÷ 2 ml = 2.5 mg/ml = 2,500 mcg/ml
Using a U100 insulin syringe (0.3 ml capacity, 100 units = 1 ml):
At 200 mcg three times daily (600 mcg/day), one 5 mg vial lasts approximately 8 days. At 200 mcg twice daily (400 mcg/day), the same vial lasts approximately 12 days.
With 2 mg peptide and 2 ml BAC water, the concentration is 1 mg/ml (1,000 mcg/ml):
For instant volume calculations based on your exact vial size, reconstitution volume, and target dose, use the BergdorfBio Peptide Calculator. Enter your parameters to get the precise draw volume in both milliliters and insulin units.
Ipamorelin is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before injection. You will need:
Use only bacteriostatic water or water for injection (WFI). Do not use tap water, commercially available distilled water, or saline solutions not specifically intended for injection use. Incorrect solvents can degrade the peptide or introduce contaminants.
Ipamorelin has one of the most favorable tolerability profiles among peptide GH secretagogues. Clinical studies and research protocols consistently report low rates of adverse events at standard doses.
Unlike GHRP-2, Ipamorelin does not produce clinically meaningful cortisol or prolactin elevation at research doses. Unlike GHRP-6, it does not induce significant appetite stimulation via central ghrelin receptor activation. This selectivity is a core safety advantage that distinguishes Ipamorelin from earlier-generation GHRPs.
Stop immediately and consult a physician if you experience persistent swelling, severe or worsening headache, visual disturbances, joint pain beyond normal soreness, or any other unusual or concerning symptoms.
The combination of Ipamorelin with CJC-1295 No DAC is the most studied and most widely used growth hormone peptide protocol. The rationale is mechanistic synergy: CJC-1295 No DAC activates the GHRH receptor on pituitary somatotrophs, while Ipamorelin simultaneously activates GHS-R1a. These two pathways converge to produce a substantially larger GH pulse than either peptide achieves alone — an effect consistent across preclinical models and observational research.
The pairing is particularly well-suited because Ipamorelin's selectivity (no cortisol, no prolactin elevation) maintains a clean hormonal backdrop that complements CJC-1295's GHRH-mediated stimulation. The two peptides are chemically compatible and can be drawn into the same insulin syringe for a single injection.
For research focused on fat metabolism and body recomposition, AOD-9604 (a modified fragment of GH, residues 176–191) can be added. AOD-9604 acts directly on adipocytes to stimulate lipolysis and inhibit lipogenesis without activating the full GH axis or elevating IGF-1. When combined with Ipamorelin, the protocol covers both the central GH pulsatility (via GHS-R1a activation) and the peripheral lipolytic pathway (via the AOD-9604 fragment).
This three-peptide protocol combines GHRH receptor stimulation (CJC-1295 No DAC), ghrelin receptor activation (Ipamorelin), and direct lipolysis (AOD-9604). It addresses GH pulsatility, IGF-1 elevation, and fat-cell metabolism through independent but complementary mechanisms. Experienced researchers may find this stack produces synergistic outcomes for body composition, recovery, and sleep quality — but it demands careful protocol design and physician-supervised monitoring.
Ipamorelin is available at BergdorfBio in 2 mg and 5 mg research-grade vials with verified purity and identity testing.
All three bind to GHS-R1a but differ critically in receptor selectivity. GHRP-2 produces significant elevations in both cortisol and prolactin alongside GH — an undesirable profile for most research applications. GHRP-6 is a potent appetite stimulant via central ghrelin receptor activation in the hypothalamus. Ipamorelin does neither at research doses. Its selectivity for pituitary somatotrophs over other GHS-R1a-expressing tissues makes it the cleanest available GHRP for combination protocols.
Yes. Both peptides are chemically compatible. Draw the first peptide into the insulin syringe, then add the second. Inject subcutaneously immediately after mixing. Do not store pre-mixed peptide solutions — mix fresh for each injection.
The two most effective windows are: (1) immediately upon waking, before any food intake or carbohydrate consumption; and (2) 30–60 minutes before sleep. Both windows align with naturally low insulin levels — insulin strongly suppresses pituitary GH responsiveness, so minimizing post-meal insulin is critical for maximizing GH pulse amplitude. Avoid injecting within 2 hours of a carbohydrate-heavy meal.
Improved sleep quality and faster exercise recovery are typically the earliest reported effects, often within 2–3 weeks. Measurable changes in body composition — increased muscle definition, reduced subcutaneous fat — generally emerge after 8–12 weeks. This timeline reflects the gradual accumulation and sustained elevation of IGF-1 required for tissue-level remodeling. Baseline and follow-up IGF-1 blood tests at 4–6 weeks provide objective confirmation of response.
No. Ipamorelin works by amplifying the pituitary's own capacity to secrete GH in response to physiological stimuli — it does not introduce exogenous GH. Unlike synthetic GH administration, there is no established mechanism for Ipamorelin to suppress the hypothalamic-pituitary axis. That said, prolonged continuous use may theoretically cause some degree of GHS-R1a desensitization. Standard protocol practice of cycling 8–12 weeks on with 4-week breaks is considered a reasonable precaution.
Strongly recommended. Establishing baseline IGF-1 levels allows monitoring of treatment response and ensures IGF-1 does not exceed the upper limit of normal — chronically elevated IGF-1 carries health risks including association with certain malignancies. A physician can also screen for contraindications (pituitary disorders, diabetes, active cancer) that would make Ipamorelin use inappropriate.
Ipamorelin is administered subcutaneously (SC) — injected into the subcutaneous fat layer just beneath the skin. Common injection sites include the lateral abdomen (flanks, away from the navel), the anterior thigh, and the triceps region. Insert the syringe at a 45°–90° angle depending on subcutaneous fat depth. Rotate sites with each injection to prevent local tissue reactions.
BergdorfBio offers Ipamorelin in verified research quality in both 2 mg and 5 mg vials. Each batch is tested for identity and purity. Visit the product page for current availability and pricing.
Legal status varies by jurisdiction. In most countries Ipamorelin is not approved as a pharmaceutical drug for human therapeutic use and is classified as a research chemical. It is prohibited in competitive sports under WADA regulations. Verify the applicable regulations in your country before purchasing or using this compound.
Disclaimer: This content is for informational and research purposes only. Ipamorelin is not an approved drug for human therapeutic use. The applications described have not been evaluated or approved by the FDA, EMA, or any other regulatory authority. Do not use peptides without the supervision of a qualified medical professional.
Pulbrist valmis süstlani viie sammuga. Ülalolev kalkulaator annab kogused automaatselt.
Lase viaalil ja veel jõuda toatemperatuurini. Pühi mõlemad kummikorgid alkoholilapiga.
Tõmba kalkulaatori soovitatud BAC-vee kogus suurema süstlaga.
Lase veel voolata mööda peptiidiviaali siseseina, ära pihusta seda otse pulbrile.
Keeruta viaali õrnalt, ära raputa. Pulber lahustub selgeks 1-2 minuti jooksul.
Tõmba insuliinisüstlaga täpselt arvutatud kriipsuni. Valmis.
Tavalised algväärtused orienteerumiseks. Iga rida avab selle peptiidi kalkulaatori.
| Peptiid | Kategooria | Tavaline annus | Viaalisuurused | BAC (algus) | Saadaval | Arvuta |
|---|---|---|---|---|---|---|
| VIP | Neuropeptiidide uurimine | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Cagrilintide | Amüliini analoog | - | 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHK-Cu | Vaskepeptiid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Ainult kalkulaator | Arvuta |
| AHK-Cu | Vaskepeptiid | - | 100 mg | 5 ml | Ainult kalkulaator | Arvuta |
| BPC-157 | Kudede taastamine | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| CJC-1295 (ilma DAC-ta) | GHRH analoog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| AOD-9604 | Rasvade ainevahetus | 250-500 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| MOTS-c | Mitokondriaalne | 5-10 mg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Selank | Anksiolüütiline | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Ainult kalkulaator | Arvuta |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Ainult kalkulaator | Arvuta |
| Melanotan II | Melanokortiin | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Melanotan I | Melanokortiin | - | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Sermorelin | GHRH analoog | 50-300 mcg | 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Tesamorelin | GHRH analoog | 1-2 mg | 10 / 20 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Thymosin Alpha-1 | Tüümusepetiid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
| Epithalon | Pikaajalisus | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Ainult kalkulaator | Arvuta |
| KPV | Immuunsüsteem / barjäär | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH Fragment 176-191 | Metaboolne fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Semax | Kognitiivne | 100-1000 mcg | 10 / 30 mg | 2 ml | Ainult kalkulaator | Arvuta |
| N-Acetyl Semax | Kognitiivne | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| DSIP | Uni | 50-500 mcg | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| 5-Amino-1MQ | Metaboolne | 2,5-10 mg | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Pinealon | Uurimispeptiid | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Survodutide | GLP-1/glükagoon | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH 191AA | Kasvuhormoon | 1-5 mg | 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
| NAD+ | Pikaajalisus / kofaktor | 100-500 mg | 1000 mg | 10 ml | Ainult kalkulaator | Arvuta |
Väärtused on mõeldud orienteerumiseks uurimiskontekstis ega asenda professionaalset nõuannet.
Kontsentratsiooni ja süstemahu õige arvutamine tundub tühine, kuid on kõige sagedasem veaallikas. Isegi 10 % suurune arvutusviga lahuse valmistamisel tähendab, et saad kas liiga vähe toimeainet või manustad kogemata üleannuse.
Lüofiliseeritud peptiide müüakse milligrammides ja need lahustatakse bakteriostaatilises vees (BAC-vesi). Peptiidi ja vee suhe määrab kontsentratsiooni ja sellest tuleneb, mitu ühikut insuliinisüstlale tõmbad. Insuliinisüstlaid gradueeritakse ühikutes, mitte milligrammides. Kalkulaator teeb selle ümberarvutuse ära, sealhulgas mõistlikkuse kontrolli kõige ohtlikuma vea vastu: mg ja mcg segiajamine.
Milligramm (mg) on ühik, milles lüofiliseeritud peptiide müüakse, näiteks „5 mg BPC-157". Mikrogramm (mcg) mõõdab üksikannust, näiteks „250 mcg süsti kohta". 1 mg = 1000 mcg. Kalkulaator teeb ümberarvutuse automaatselt ja hoiatab, kui sisestus tundub segiaetud olevat.
U-100 tähendab, et süstal on kalibreeritud 100 ühikule milliliitri kohta. 100 IU = 1 ml, seega 10 IU = 0,10 ml, sõltumata sellest, mis süstlas on. IU arvutus põhineb täpselt sellel seosel.
Palju peptiidi ja vähe vett teeb lahuse väga kontsentreerituks, mistõttu maht annuse kohta on tilluke ja raskesti loetav. Kasuta segamise abivahendit: see leiab veekoguse, millega tekib puhas ja hästi loetav kriips.
Külmkapis 2-8 °C juures tavaliselt 21-30 päeva. Märgista viaalile lahuse valmistamise kuupäev. Hägused lahused või osakesed ei kõlba.
Segud sisaldavad ühes viaalis mitut toimeainet. Vali peptiidiks lihtsalt segu: kalkulaator näitab lisaks, kui palju igat komponenti sinu süstis on. Mitme eraldi viaali kombinatsiooni jaoks kasuta Stack Builderit.
Ei. Sinu viimased seaded salvestatakse lokaalselt brauserisse ja taastatakse järgmisel külastusel. Arvutusi saad ka ajaloost tagasi kutsuda, protokollina salvestada või lingina jagada.
Vali peptiid, et avada selle kalkulaatorileht eeltäidetud väärtustega.
Laos
Laos
Vaata toodet
IpamorelinVaata toodet
IpamorelinTavalised algväärtused orienteerumiseks. Iga rida avab selle peptiidi kalkulaatori.
| Peptiid | Kategooria | Tavaline annus | Viaalisuurused | BAC (algus) | Saadaval | Arvuta |
|---|---|---|---|---|---|---|
| VIP | Neuropeptiidide uurimine | - | 10 mg | 2 ml | Laos | Arvuta |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Laos | Arvuta |
| Cagrilintide | Amüliini analoog | - | 5 mg | 2 ml | Laos | Arvuta |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Laos | Arvuta |
| GHK-Cu | Vaskepeptiid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Laos | Arvuta |
| AHK-Cu | Vaskepeptiid | - | 100 mg | 5 ml | Laos | Arvuta |
| BPC-157 | Kudede taastamine | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| CJC-1295 (ilma DAC-ta) | GHRH analoog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Laos | Arvuta |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| MOTS-c | Mitokondriaalne | 5-10 mg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Selank | Anksiolüütiline | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Laos | Arvuta |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Laos | Arvuta |
| Melanotan II | Melanokortiin | 100-1000 mcg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Melanotan I | Melanokortiin | - | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Sermorelin | GHRH analoog | 50-300 mcg | 5 mg | 2 ml | Laos | Arvuta |
| Tesamorelin | GHRH analoog | 1-2 mg | 10 / 20 mg | 2 ml | Laos | Arvuta |
| Thymosin Alpha-1 | Tüümusepetiid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Laos | Arvuta |
| Epithalon | Pikaajalisus | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Laos | Arvuta |
| KPV | Immuunsüsteem / barjäär | 100-1000 mcg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Semax | Kognitiivne | 100-1000 mcg | 10 / 30 mg | 2 ml | Laos | Arvuta |
| DSIP | Uni | 50-500 mcg | 10 mg | 2 ml | Laos | Arvuta |
| 5-Amino-1MQ | Metaboolne | 2,5-10 mg | 10 mg | 2 ml | Laos | Arvuta |
| Pinealon | Uurimispeptiid | - | 10 mg | 2 ml | Laos | Arvuta |
| Survodutide | GLP-1/glükagoon | - | 10 mg | 2 ml | Laos | Arvuta |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Laos | Arvuta |
| NAD+ | Pikaajalisus / kofaktor | 100-500 mg | 1000 mg | 10 ml | Laos | Arvuta |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| AOD-9604 | Rasvade ainevahetus | 250-500 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH Fragment 176-191 | Metaboolne fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| N-Acetyl Semax | Kognitiivne | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH 191AA | Kasvuhormoon | 1-5 mg | 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
Väärtused on mõeldud orienteerumiseks uurimiskontekstis ega asenda professionaalset nõuannet.
Tavalised algväärtused orienteerumiseks. Iga rida avab selle peptiidi kalkulaatori.
| Peptiid | Kategooria | Tavaline annus | Viaalisuurused | BAC (algus) | Saadaval | Arvuta |
|---|---|---|---|---|---|---|
| VIP | Neuropeptiidide uurimine | - | 10 mg | 2 ml | Laos | Arvuta |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Laos | Arvuta |
| Cagrilintide | Amüliini analoog | - | 5 mg | 2 ml | Laos | Arvuta |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Laos | Arvuta |
| GHK-Cu | Vaskepeptiid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Laos | Arvuta |
| AHK-Cu | Vaskepeptiid | - | 100 mg | 5 ml | Laos | Arvuta |
| BPC-157 | Kudede taastamine | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| CJC-1295 (ilma DAC-ta) | GHRH analoog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Laos | Arvuta |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| MOTS-c | Mitokondriaalne | 5-10 mg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Selank | Anksiolüütiline | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Laos | Arvuta |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Laos | Arvuta |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Laos | Arvuta |
| Melanotan II | Melanokortiin | 100-1000 mcg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Melanotan I | Melanokortiin | - | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Sermorelin | GHRH analoog | 50-300 mcg | 5 mg | 2 ml | Laos | Arvuta |
| Tesamorelin | GHRH analoog | 1-2 mg | 10 / 20 mg | 2 ml | Laos | Arvuta |
| Thymosin Alpha-1 | Tüümusepetiid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Laos | Arvuta |
| Epithalon | Pikaajalisus | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Laos | Arvuta |
| KPV | Immuunsüsteem / barjäär | 100-1000 mcg | 5 / 10 mg | 2 ml | Laos | Arvuta |
| Semax | Kognitiivne | 100-1000 mcg | 10 / 30 mg | 2 ml | Laos | Arvuta |
| DSIP | Uni | 50-500 mcg | 10 mg | 2 ml | Laos | Arvuta |
| 5-Amino-1MQ | Metaboolne | 2,5-10 mg | 10 mg | 2 ml | Laos | Arvuta |
| Pinealon | Uurimispeptiid | - | 10 mg | 2 ml | Laos | Arvuta |
| Survodutide | GLP-1/glükagoon | - | 10 mg | 2 ml | Laos | Arvuta |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Laos | Arvuta |
| NAD+ | Pikaajalisus / kofaktor | 100-500 mg | 1000 mg | 10 ml | Laos | Arvuta |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| AOD-9604 | Rasvade ainevahetus | 250-500 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH Fragment 176-191 | Metaboolne fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| N-Acetyl Semax | Kognitiivne | 100-1000 mcg | 5 / 10 mg | 2 ml | Ainult kalkulaator | Arvuta |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Ainult kalkulaator | Arvuta |
| HGH 191AA | Kasvuhormoon | 1-5 mg | 10 mg | 1 ml | Ainult kalkulaator | Arvuta |
Väärtused on mõeldud orienteerumiseks uurimiskontekstis ega asenda professionaalset nõuannet.
Vali peptiid, et avada selle kalkulaatorileht eeltäidetud väärtustega.
Vali peptiid, et avada selle kalkulaatorileht eeltäidetud väärtustega.