

Izračunajte natančne volumne rekonstitucije, inzulinske enote in odmerke na stekleničko za vsak peptid.
Steklenička, voda in odmerek so znani
Enote merijo volumen, ne učinkovino. 8 IU = 0,08 ml. Koliko mg je v tem, je odvisno od mešanice. Kalkulator je to izračunal namesto Vas.
Skoraj vse inzulinske brizge so U-100. U-40 izberite le, če je na brizgi oznaka U-40.
Povezani viri vodijo na PubMed in se odprejo v novem zavihku.
Znanstveni profil
Ipamorelin v leksikonu peptidov: mehanizem, dokazi in viri
Dopolnilno orodje
Poglejte, kako dolgo Ipamorelin ostane v telesu
Ipamorelin is a synthetic pentapeptide growth hormone-releasing peptide (GHRP) widely regarded as the most selective GH secretagogue available in research. Unlike older GHRPs, it stimulates growth hormone release without significantly raising cortisol or prolactin. This guide covers everything you need: mechanism of action, dosage calculation, reconstitution protocol, storage, safety profile, and how to effectively combine Ipamorelin with CJC-1295 No DAC and other peptides.
Medical Disclaimer: The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Peptides are not approved drugs for human use. Always consult a qualified healthcare provider before using peptides.
Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. Originally developed at Novo Nordisk in the 1990s, it underwent Phase II clinical trials for postoperative ileus and growth hormone deficiency. Though it never reached pharmaceutical approval, Ipamorelin became one of the most extensively studied GHRPs in biomedical research and remains a benchmark compound in its class.
Structurally, Ipamorelin belongs to the family of ghrelin mimetics. It binds to the growth hormone secretagogue receptor type 1a (GHS-R1a), expressed in both the anterior pituitary and the hypothalamus. What distinguishes Ipamorelin from earlier compounds such as GHRP-2 and GHRP-6 is its receptor selectivity: at research doses, it produces robust GH release without meaningful stimulation of cortisol, ACTH, or prolactin — a profile that makes it uniquely well-tolerated and suitable for combination protocols.
Ipamorelin activates GHS-R1a receptors on somatotroph cells in the anterior pituitary. This triggers intracellular calcium mobilization via the phospholipase C/IP₃ pathway, stimulating the pulsatile secretion of growth hormone. Concurrently, Ipamorelin suppresses somatostatin — the hypothalamic inhibitor of GH release — amplifying the net GH pulse.
The resulting GH elevation drives hepatic IGF-1 (Insulin-like Growth Factor 1) production, which mediates the downstream anabolic and lipolytic effects associated with GH axis activation. Potential effects include:
The defining feature of Ipamorelin is its selectivity for somatotroph GH release over other neuroendocrine axes. GHRP-2 produces significant cortisol and prolactin elevations alongside GH — complicating protocols that require stress-hormone neutrality. GHRP-6 powerfully stimulates appetite via central ghrelin receptors. Ipamorelin shows neither effect at clinically relevant doses. This selectivity is not incidental but results from its specific structural affinity for the GHS-R1a subtype expressed in the pituitary, without meaningful cross-reactivity at other receptor populations. For researchers designing multi-peptide protocols, this clean pharmacological profile simplifies interpretation of outcomes and reduces confounding variables.
Accurate dosage calculation is critical for both efficacy and safety. Standard dosing parameters for Ipamorelin are:
Ipamorelin does not require a titration phase. The standard dose can be used from the first injection, though some practitioners prefer starting at the lower end of the range (200 mcg) for the first week to assess individual response.
The standard BergdorfBio Ipamorelin vial contains 5 mg of lyophilized peptide. Adding 2 ml of bacteriostatic water (BAC water) yields a concentration of:
5 mg ÷ 2 ml = 2.5 mg/ml = 2,500 mcg/ml
Using a U100 insulin syringe (0.3 ml capacity, 100 units = 1 ml):
At 200 mcg three times daily (600 mcg/day), one 5 mg vial lasts approximately 8 days. At 200 mcg twice daily (400 mcg/day), the same vial lasts approximately 12 days.
With 2 mg peptide and 2 ml BAC water, the concentration is 1 mg/ml (1,000 mcg/ml):
For instant volume calculations based on your exact vial size, reconstitution volume, and target dose, use the BergdorfBio Peptide Calculator. Enter your parameters to get the precise draw volume in both milliliters and insulin units.
Ipamorelin is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before injection. You will need:
Use only bacteriostatic water or water for injection (WFI). Do not use tap water, commercially available distilled water, or saline solutions not specifically intended for injection use. Incorrect solvents can degrade the peptide or introduce contaminants.
Ipamorelin has one of the most favorable tolerability profiles among peptide GH secretagogues. Clinical studies and research protocols consistently report low rates of adverse events at standard doses.
Unlike GHRP-2, Ipamorelin does not produce clinically meaningful cortisol or prolactin elevation at research doses. Unlike GHRP-6, it does not induce significant appetite stimulation via central ghrelin receptor activation. This selectivity is a core safety advantage that distinguishes Ipamorelin from earlier-generation GHRPs.
Stop immediately and consult a physician if you experience persistent swelling, severe or worsening headache, visual disturbances, joint pain beyond normal soreness, or any other unusual or concerning symptoms.
The combination of Ipamorelin with CJC-1295 No DAC is the most studied and most widely used growth hormone peptide protocol. The rationale is mechanistic synergy: CJC-1295 No DAC activates the GHRH receptor on pituitary somatotrophs, while Ipamorelin simultaneously activates GHS-R1a. These two pathways converge to produce a substantially larger GH pulse than either peptide achieves alone — an effect consistent across preclinical models and observational research.
The pairing is particularly well-suited because Ipamorelin's selectivity (no cortisol, no prolactin elevation) maintains a clean hormonal backdrop that complements CJC-1295's GHRH-mediated stimulation. The two peptides are chemically compatible and can be drawn into the same insulin syringe for a single injection.
For research focused on fat metabolism and body recomposition, AOD-9604 (a modified fragment of GH, residues 176–191) can be added. AOD-9604 acts directly on adipocytes to stimulate lipolysis and inhibit lipogenesis without activating the full GH axis or elevating IGF-1. When combined with Ipamorelin, the protocol covers both the central GH pulsatility (via GHS-R1a activation) and the peripheral lipolytic pathway (via the AOD-9604 fragment).
This three-peptide protocol combines GHRH receptor stimulation (CJC-1295 No DAC), ghrelin receptor activation (Ipamorelin), and direct lipolysis (AOD-9604). It addresses GH pulsatility, IGF-1 elevation, and fat-cell metabolism through independent but complementary mechanisms. Experienced researchers may find this stack produces synergistic outcomes for body composition, recovery, and sleep quality — but it demands careful protocol design and physician-supervised monitoring.
Ipamorelin is available at BergdorfBio in 2 mg and 5 mg research-grade vials with verified purity and identity testing.
All three bind to GHS-R1a but differ critically in receptor selectivity. GHRP-2 produces significant elevations in both cortisol and prolactin alongside GH — an undesirable profile for most research applications. GHRP-6 is a potent appetite stimulant via central ghrelin receptor activation in the hypothalamus. Ipamorelin does neither at research doses. Its selectivity for pituitary somatotrophs over other GHS-R1a-expressing tissues makes it the cleanest available GHRP for combination protocols.
Yes. Both peptides are chemically compatible. Draw the first peptide into the insulin syringe, then add the second. Inject subcutaneously immediately after mixing. Do not store pre-mixed peptide solutions — mix fresh for each injection.
The two most effective windows are: (1) immediately upon waking, before any food intake or carbohydrate consumption; and (2) 30–60 minutes before sleep. Both windows align with naturally low insulin levels — insulin strongly suppresses pituitary GH responsiveness, so minimizing post-meal insulin is critical for maximizing GH pulse amplitude. Avoid injecting within 2 hours of a carbohydrate-heavy meal.
Improved sleep quality and faster exercise recovery are typically the earliest reported effects, often within 2–3 weeks. Measurable changes in body composition — increased muscle definition, reduced subcutaneous fat — generally emerge after 8–12 weeks. This timeline reflects the gradual accumulation and sustained elevation of IGF-1 required for tissue-level remodeling. Baseline and follow-up IGF-1 blood tests at 4–6 weeks provide objective confirmation of response.
No. Ipamorelin works by amplifying the pituitary's own capacity to secrete GH in response to physiological stimuli — it does not introduce exogenous GH. Unlike synthetic GH administration, there is no established mechanism for Ipamorelin to suppress the hypothalamic-pituitary axis. That said, prolonged continuous use may theoretically cause some degree of GHS-R1a desensitization. Standard protocol practice of cycling 8–12 weeks on with 4-week breaks is considered a reasonable precaution.
Strongly recommended. Establishing baseline IGF-1 levels allows monitoring of treatment response and ensures IGF-1 does not exceed the upper limit of normal — chronically elevated IGF-1 carries health risks including association with certain malignancies. A physician can also screen for contraindications (pituitary disorders, diabetes, active cancer) that would make Ipamorelin use inappropriate.
Ipamorelin is administered subcutaneously (SC) — injected into the subcutaneous fat layer just beneath the skin. Common injection sites include the lateral abdomen (flanks, away from the navel), the anterior thigh, and the triceps region. Insert the syringe at a 45°–90° angle depending on subcutaneous fat depth. Rotate sites with each injection to prevent local tissue reactions.
BergdorfBio offers Ipamorelin in verified research quality in both 2 mg and 5 mg vials. Each batch is tested for identity and purity. Visit the product page for current availability and pricing.
Legal status varies by jurisdiction. In most countries Ipamorelin is not approved as a pharmaceutical drug for human therapeutic use and is classified as a research chemical. It is prohibited in competitive sports under WADA regulations. Verify the applicable regulations in your country before purchasing or using this compound.
Disclaimer: This content is for informational and research purposes only. Ipamorelin is not an approved drug for human therapeutic use. The applications described have not been evaluated or approved by the FDA, EMA, or any other regulatory authority. Do not use peptides without the supervision of a qualified medical professional.
Od praška do pripravljene brizge v petih korakih. Kalkulator zgoraj Vam količine izračuna samodejno.
Stekleničko in vodo segrejte na sobno temperaturo. Oba gumijasta zamaška obrišite z alkoholno blazinico.
Z večjo brizgo nategnite količino BAC vode, ki jo priporoča kalkulator.
Vodo spustite po notranji steni stekleničke s peptidom, ne pršite je neposredno na prašek.
Stekleničko nežno vrtite, ne stresajte. Prašek se raztopi v bistro raztopino v 1-2 minutah.
Z inzulinsko brizgo nategnite točno do izračunane oznake. Končano.
Običajne začetne vrednosti za orientacijo. Vsaka vrstica odpre kalkulator za ta peptid.
| Peptid | Kategorija | Običajen odmerek | Velikosti stekleničk | BAC (začetek) | Na voljo | Izračun |
|---|---|---|---|---|---|---|
| VIP | Raziskovanje nevropeptidov | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Samo kalkulator | Izračunaj |
| Cagrilintide | Analog amilina | - | 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHK-Cu | Bakrov peptid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Samo kalkulator | Izračunaj |
| AHK-Cu | Bakrov peptid | - | 100 mg | 5 ml | Samo kalkulator | Izračunaj |
| BPC-157 | Obnova tkiva | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| CJC-1295 (brez DAC) | GHRH analog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| AOD-9604 | Izguba maščobe | 250-500 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| MOTS-c | Mitohondrijski | 5-10 mg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Selank | Anksiolitik | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Samo kalkulator | Izračunaj |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Samo kalkulator | Izračunaj |
| Melanotan II | Melanokortin | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Melanotan I | Melanokortin | - | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Sermorelin | GHRH analog | 50-300 mcg | 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| Tesamorelin | GHRH analog | 1-2 mg | 10 / 20 mg | 2 ml | Samo kalkulator | Izračunaj |
| Thymosin Alpha-1 | Timusni peptid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Samo kalkulator | Izračunaj |
| Epithalon | Dolgoživost | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Samo kalkulator | Izračunaj |
| KPV | Imunski sistem / pregrada | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH Fragment 176-191 | Presnovni fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Semax | Kognitivno | 100-1000 mcg | 10 / 30 mg | 2 ml | Samo kalkulator | Izračunaj |
| N-Acetyl Semax | Kognitivno | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| DSIP | Spanje | 50-500 mcg | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| 5-Amino-1MQ | Presnovno | 2,5-10 mg | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Pinealon | Raziskovalni peptid | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Survodutide | GLP-1/glukagon | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH 191AA | Rastni hormon | 1-5 mg | 10 mg | 1 ml | Samo kalkulator | Izračunaj |
| NAD+ | Dolgoživost / kofaktor | 100-500 mg | 1000 mg | 10 ml | Samo kalkulator | Izračunaj |
Vrednosti so za orientacijo v raziskovalnem kontekstu in ne nadomeščajo strokovnega nasveta.
Pravilen izračun koncentracije in volumna injekcije se zdi samoumeven, a je najpogostejši vir napak. Že 10 % napačen izračun pri rekonstituciji pomeni, da dobite premalo učinkovine ali pa nenamerno prevelik odmerek.
Liofilizirani peptidi so dobavljeni v miligramih in raztopljeni v bakteriostatični vodi (BAC voda). Razmerje med peptidom in vodo določa koncentracijo, iz nje pa izhaja, koliko enot nategnete na inzulinski brizgi. Inzulinske brizge so graduirane v enotah, ne v miligramih. Kalkulator to pretvorbo opravi namesto Vas, vključno s preverjanjem smiselnosti proti najnevarnejši napaki: zamenjavi mg in mcg.
Miligrami (mg) so enota, v kateri se prodajajo liofilizirani peptidi, na primer »5 mg BPC-157«. Mikrogrami (mcg) merijo posamezni odmerek, na primer »250 mcg na injekcijo«. 1 mg = 1.000 mcg. Kalkulator pretvarja samodejno in opozori, kadar je vnos videti kot zamenjava.
U-100 pomeni, da je brizga umerjena na 100 enot na mililiter. 100 IU = 1 ml, torej 10 IU = 0,10 ml, ne glede na to, kaj je v brizgi. Izračun IU temelji točno na tem razmerju.
Ob veliko peptida in malo vode postane raztopina zelo koncentrirana, zato je volumen na odmerek majhen in težko odčitljiv. Uporabite pomoč pri mešanju: poišče volumen vode, ki da čisto, lahko berljivo oznako.
V hladilniku pri 2-8 °C običajno 21-30 dni. Stekleničko označite z datumom rekonstitucije. Motne raztopine ali delci niso sprejemljivi.
Mešanice vsebujejo več učinkovin v eni steklenički. Kot peptid preprosto izberite mešanico: kalkulator dodatno pokaže, koliko posamezne sestavine je v Vaši injekciji. Za kombinacije več ločenih stekleničk uporabite sestavljalnik kombinacij.
Ne. Vaše zadnje nastavitve se shranijo lokalno v brskalniku in obnovijo ob naslednjem obisku. Izračune lahko tudi prikličete iz zgodovine, jih shranite kot protokol ali delite s povezavo.
Izberite peptid in odprla se bo njegova stran kalkulatorja z že izpolnjenimi vrednostmi.
Izračunajte natančne volumne rekonstitucije, inzulinske enote in odmerke na stekleničko za vsak peptid.
Steklenička, voda in odmerek so znani
Enote merijo volumen, ne učinkovino. 8 IU = 0,08 ml. Koliko mg je v tem, je odvisno od mešanice. Kalkulator je to izračunal namesto Vas.
Skoraj vse inzulinske brizge so U-100. U-40 izberite le, če je na brizgi oznaka U-40.
Povezani viri vodijo na PubMed in se odprejo v novem zavihku.
Znanstveni profil
Ipamorelin v leksikonu peptidov: mehanizem, dokazi in viri
Dopolnilno orodje
Poglejte, kako dolgo Ipamorelin ostane v telesu
Ipamorelin is a synthetic pentapeptide growth hormone-releasing peptide (GHRP) widely regarded as the most selective GH secretagogue available in research. Unlike older GHRPs, it stimulates growth hormone release without significantly raising cortisol or prolactin. This guide covers everything you need: mechanism of action, dosage calculation, reconstitution protocol, storage, safety profile, and how to effectively combine Ipamorelin with CJC-1295 No DAC and other peptides.
Medical Disclaimer: The content on this page is for informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Peptides are not approved drugs for human use. Always consult a qualified healthcare provider before using peptides.
Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. Originally developed at Novo Nordisk in the 1990s, it underwent Phase II clinical trials for postoperative ileus and growth hormone deficiency. Though it never reached pharmaceutical approval, Ipamorelin became one of the most extensively studied GHRPs in biomedical research and remains a benchmark compound in its class.
Structurally, Ipamorelin belongs to the family of ghrelin mimetics. It binds to the growth hormone secretagogue receptor type 1a (GHS-R1a), expressed in both the anterior pituitary and the hypothalamus. What distinguishes Ipamorelin from earlier compounds such as GHRP-2 and GHRP-6 is its receptor selectivity: at research doses, it produces robust GH release without meaningful stimulation of cortisol, ACTH, or prolactin — a profile that makes it uniquely well-tolerated and suitable for combination protocols.
Ipamorelin activates GHS-R1a receptors on somatotroph cells in the anterior pituitary. This triggers intracellular calcium mobilization via the phospholipase C/IP₃ pathway, stimulating the pulsatile secretion of growth hormone. Concurrently, Ipamorelin suppresses somatostatin — the hypothalamic inhibitor of GH release — amplifying the net GH pulse.
The resulting GH elevation drives hepatic IGF-1 (Insulin-like Growth Factor 1) production, which mediates the downstream anabolic and lipolytic effects associated with GH axis activation. Potential effects include:
The defining feature of Ipamorelin is its selectivity for somatotroph GH release over other neuroendocrine axes. GHRP-2 produces significant cortisol and prolactin elevations alongside GH — complicating protocols that require stress-hormone neutrality. GHRP-6 powerfully stimulates appetite via central ghrelin receptors. Ipamorelin shows neither effect at clinically relevant doses. This selectivity is not incidental but results from its specific structural affinity for the GHS-R1a subtype expressed in the pituitary, without meaningful cross-reactivity at other receptor populations. For researchers designing multi-peptide protocols, this clean pharmacological profile simplifies interpretation of outcomes and reduces confounding variables.
Accurate dosage calculation is critical for both efficacy and safety. Standard dosing parameters for Ipamorelin are:
Ipamorelin does not require a titration phase. The standard dose can be used from the first injection, though some practitioners prefer starting at the lower end of the range (200 mcg) for the first week to assess individual response.
The standard BergdorfBio Ipamorelin vial contains 5 mg of lyophilized peptide. Adding 2 ml of bacteriostatic water (BAC water) yields a concentration of:
5 mg ÷ 2 ml = 2.5 mg/ml = 2,500 mcg/ml
Using a U100 insulin syringe (0.3 ml capacity, 100 units = 1 ml):
At 200 mcg three times daily (600 mcg/day), one 5 mg vial lasts approximately 8 days. At 200 mcg twice daily (400 mcg/day), the same vial lasts approximately 12 days.
With 2 mg peptide and 2 ml BAC water, the concentration is 1 mg/ml (1,000 mcg/ml):
For instant volume calculations based on your exact vial size, reconstitution volume, and target dose, use the BergdorfBio Peptide Calculator. Enter your parameters to get the precise draw volume in both milliliters and insulin units.
Ipamorelin is supplied as a lyophilized (freeze-dried) powder and must be reconstituted before injection. You will need:
Use only bacteriostatic water or water for injection (WFI). Do not use tap water, commercially available distilled water, or saline solutions not specifically intended for injection use. Incorrect solvents can degrade the peptide or introduce contaminants.
Ipamorelin has one of the most favorable tolerability profiles among peptide GH secretagogues. Clinical studies and research protocols consistently report low rates of adverse events at standard doses.
Unlike GHRP-2, Ipamorelin does not produce clinically meaningful cortisol or prolactin elevation at research doses. Unlike GHRP-6, it does not induce significant appetite stimulation via central ghrelin receptor activation. This selectivity is a core safety advantage that distinguishes Ipamorelin from earlier-generation GHRPs.
Stop immediately and consult a physician if you experience persistent swelling, severe or worsening headache, visual disturbances, joint pain beyond normal soreness, or any other unusual or concerning symptoms.
The combination of Ipamorelin with CJC-1295 No DAC is the most studied and most widely used growth hormone peptide protocol. The rationale is mechanistic synergy: CJC-1295 No DAC activates the GHRH receptor on pituitary somatotrophs, while Ipamorelin simultaneously activates GHS-R1a. These two pathways converge to produce a substantially larger GH pulse than either peptide achieves alone — an effect consistent across preclinical models and observational research.
The pairing is particularly well-suited because Ipamorelin's selectivity (no cortisol, no prolactin elevation) maintains a clean hormonal backdrop that complements CJC-1295's GHRH-mediated stimulation. The two peptides are chemically compatible and can be drawn into the same insulin syringe for a single injection.
For research focused on fat metabolism and body recomposition, AOD-9604 (a modified fragment of GH, residues 176–191) can be added. AOD-9604 acts directly on adipocytes to stimulate lipolysis and inhibit lipogenesis without activating the full GH axis or elevating IGF-1. When combined with Ipamorelin, the protocol covers both the central GH pulsatility (via GHS-R1a activation) and the peripheral lipolytic pathway (via the AOD-9604 fragment).
This three-peptide protocol combines GHRH receptor stimulation (CJC-1295 No DAC), ghrelin receptor activation (Ipamorelin), and direct lipolysis (AOD-9604). It addresses GH pulsatility, IGF-1 elevation, and fat-cell metabolism through independent but complementary mechanisms. Experienced researchers may find this stack produces synergistic outcomes for body composition, recovery, and sleep quality — but it demands careful protocol design and physician-supervised monitoring.
Ipamorelin is available at BergdorfBio in 2 mg and 5 mg research-grade vials with verified purity and identity testing.
All three bind to GHS-R1a but differ critically in receptor selectivity. GHRP-2 produces significant elevations in both cortisol and prolactin alongside GH — an undesirable profile for most research applications. GHRP-6 is a potent appetite stimulant via central ghrelin receptor activation in the hypothalamus. Ipamorelin does neither at research doses. Its selectivity for pituitary somatotrophs over other GHS-R1a-expressing tissues makes it the cleanest available GHRP for combination protocols.
Yes. Both peptides are chemically compatible. Draw the first peptide into the insulin syringe, then add the second. Inject subcutaneously immediately after mixing. Do not store pre-mixed peptide solutions — mix fresh for each injection.
The two most effective windows are: (1) immediately upon waking, before any food intake or carbohydrate consumption; and (2) 30–60 minutes before sleep. Both windows align with naturally low insulin levels — insulin strongly suppresses pituitary GH responsiveness, so minimizing post-meal insulin is critical for maximizing GH pulse amplitude. Avoid injecting within 2 hours of a carbohydrate-heavy meal.
Improved sleep quality and faster exercise recovery are typically the earliest reported effects, often within 2–3 weeks. Measurable changes in body composition — increased muscle definition, reduced subcutaneous fat — generally emerge after 8–12 weeks. This timeline reflects the gradual accumulation and sustained elevation of IGF-1 required for tissue-level remodeling. Baseline and follow-up IGF-1 blood tests at 4–6 weeks provide objective confirmation of response.
No. Ipamorelin works by amplifying the pituitary's own capacity to secrete GH in response to physiological stimuli — it does not introduce exogenous GH. Unlike synthetic GH administration, there is no established mechanism for Ipamorelin to suppress the hypothalamic-pituitary axis. That said, prolonged continuous use may theoretically cause some degree of GHS-R1a desensitization. Standard protocol practice of cycling 8–12 weeks on with 4-week breaks is considered a reasonable precaution.
Strongly recommended. Establishing baseline IGF-1 levels allows monitoring of treatment response and ensures IGF-1 does not exceed the upper limit of normal — chronically elevated IGF-1 carries health risks including association with certain malignancies. A physician can also screen for contraindications (pituitary disorders, diabetes, active cancer) that would make Ipamorelin use inappropriate.
Ipamorelin is administered subcutaneously (SC) — injected into the subcutaneous fat layer just beneath the skin. Common injection sites include the lateral abdomen (flanks, away from the navel), the anterior thigh, and the triceps region. Insert the syringe at a 45°–90° angle depending on subcutaneous fat depth. Rotate sites with each injection to prevent local tissue reactions.
BergdorfBio offers Ipamorelin in verified research quality in both 2 mg and 5 mg vials. Each batch is tested for identity and purity. Visit the product page for current availability and pricing.
Legal status varies by jurisdiction. In most countries Ipamorelin is not approved as a pharmaceutical drug for human therapeutic use and is classified as a research chemical. It is prohibited in competitive sports under WADA regulations. Verify the applicable regulations in your country before purchasing or using this compound.
Disclaimer: This content is for informational and research purposes only. Ipamorelin is not an approved drug for human therapeutic use. The applications described have not been evaluated or approved by the FDA, EMA, or any other regulatory authority. Do not use peptides without the supervision of a qualified medical professional.
Od praška do pripravljene brizge v petih korakih. Kalkulator zgoraj Vam količine izračuna samodejno.
Stekleničko in vodo segrejte na sobno temperaturo. Oba gumijasta zamaška obrišite z alkoholno blazinico.
Z večjo brizgo nategnite količino BAC vode, ki jo priporoča kalkulator.
Vodo spustite po notranji steni stekleničke s peptidom, ne pršite je neposredno na prašek.
Stekleničko nežno vrtite, ne stresajte. Prašek se raztopi v bistro raztopino v 1-2 minutah.
Z inzulinsko brizgo nategnite točno do izračunane oznake. Končano.
Običajne začetne vrednosti za orientacijo. Vsaka vrstica odpre kalkulator za ta peptid.
| Peptid | Kategorija | Običajen odmerek | Velikosti stekleničk | BAC (začetek) | Na voljo | Izračun |
|---|---|---|---|---|---|---|
| VIP | Raziskovanje nevropeptidov | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Samo kalkulator | Izračunaj |
| Cagrilintide | Analog amilina | - | 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHK-Cu | Bakrov peptid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Samo kalkulator | Izračunaj |
| AHK-Cu | Bakrov peptid | - | 100 mg | 5 ml | Samo kalkulator | Izračunaj |
| BPC-157 | Obnova tkiva | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| CJC-1295 (brez DAC) | GHRH analog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| AOD-9604 | Izguba maščobe | 250-500 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| MOTS-c | Mitohondrijski | 5-10 mg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Selank | Anksiolitik | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Samo kalkulator | Izračunaj |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Samo kalkulator | Izračunaj |
| Melanotan II | Melanokortin | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Melanotan I | Melanokortin | - | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Sermorelin | GHRH analog | 50-300 mcg | 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| Tesamorelin | GHRH analog | 1-2 mg | 10 / 20 mg | 2 ml | Samo kalkulator | Izračunaj |
| Thymosin Alpha-1 | Timusni peptid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Samo kalkulator | Izračunaj |
| Epithalon | Dolgoživost | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Samo kalkulator | Izračunaj |
| KPV | Imunski sistem / pregrada | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH Fragment 176-191 | Presnovni fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Semax | Kognitivno | 100-1000 mcg | 10 / 30 mg | 2 ml | Samo kalkulator | Izračunaj |
| N-Acetyl Semax | Kognitivno | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| DSIP | Spanje | 50-500 mcg | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| 5-Amino-1MQ | Presnovno | 2,5-10 mg | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Pinealon | Raziskovalni peptid | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Survodutide | GLP-1/glukagon | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH 191AA | Rastni hormon | 1-5 mg | 10 mg | 1 ml | Samo kalkulator | Izračunaj |
| NAD+ | Dolgoživost / kofaktor | 100-500 mg | 1000 mg | 10 ml | Samo kalkulator | Izračunaj |
Vrednosti so za orientacijo v raziskovalnem kontekstu in ne nadomeščajo strokovnega nasveta.
Pravilen izračun koncentracije in volumna injekcije se zdi samoumeven, a je najpogostejši vir napak. Že 10 % napačen izračun pri rekonstituciji pomeni, da dobite premalo učinkovine ali pa nenamerno prevelik odmerek.
Liofilizirani peptidi so dobavljeni v miligramih in raztopljeni v bakteriostatični vodi (BAC voda). Razmerje med peptidom in vodo določa koncentracijo, iz nje pa izhaja, koliko enot nategnete na inzulinski brizgi. Inzulinske brizge so graduirane v enotah, ne v miligramih. Kalkulator to pretvorbo opravi namesto Vas, vključno s preverjanjem smiselnosti proti najnevarnejši napaki: zamenjavi mg in mcg.
Miligrami (mg) so enota, v kateri se prodajajo liofilizirani peptidi, na primer »5 mg BPC-157«. Mikrogrami (mcg) merijo posamezni odmerek, na primer »250 mcg na injekcijo«. 1 mg = 1.000 mcg. Kalkulator pretvarja samodejno in opozori, kadar je vnos videti kot zamenjava.
U-100 pomeni, da je brizga umerjena na 100 enot na mililiter. 100 IU = 1 ml, torej 10 IU = 0,10 ml, ne glede na to, kaj je v brizgi. Izračun IU temelji točno na tem razmerju.
Ob veliko peptida in malo vode postane raztopina zelo koncentrirana, zato je volumen na odmerek majhen in težko odčitljiv. Uporabite pomoč pri mešanju: poišče volumen vode, ki da čisto, lahko berljivo oznako.
V hladilniku pri 2-8 °C običajno 21-30 dni. Stekleničko označite z datumom rekonstitucije. Motne raztopine ali delci niso sprejemljivi.
Mešanice vsebujejo več učinkovin v eni steklenički. Kot peptid preprosto izberite mešanico: kalkulator dodatno pokaže, koliko posamezne sestavine je v Vaši injekciji. Za kombinacije več ločenih stekleničk uporabite sestavljalnik kombinacij.
Ne. Vaše zadnje nastavitve se shranijo lokalno v brskalniku in obnovijo ob naslednjem obisku. Izračune lahko tudi prikličete iz zgodovine, jih shranite kot protokol ali delite s povezavo.
Izberite peptid in odprla se bo njegova stran kalkulatorja z že izpolnjenimi vrednostmi.
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IpamorelinObičajne začetne vrednosti za orientacijo. Vsaka vrstica odpre kalkulator za ta peptid.
| Peptid | Kategorija | Običajen odmerek | Velikosti stekleničk | BAC (začetek) | Na voljo | Izračun |
|---|---|---|---|---|---|---|
| VIP | Raziskovanje nevropeptidov | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Na zalogi | Izračunaj |
| Cagrilintide | Analog amilina | - | 5 mg | 2 ml | Na zalogi | Izračunaj |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Na zalogi | Izračunaj |
| GHK-Cu | Bakrov peptid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Na zalogi | Izračunaj |
| AHK-Cu | Bakrov peptid | - | 100 mg | 5 ml | Na zalogi | Izračunaj |
| BPC-157 | Obnova tkiva | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| CJC-1295 (brez DAC) | GHRH analog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Na zalogi | Izračunaj |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| MOTS-c | Mitohondrijski | 5-10 mg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Selank | Anksiolitik | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Na zalogi | Izračunaj |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Na zalogi | Izračunaj |
| Melanotan II | Melanokortin | 100-1000 mcg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Melanotan I | Melanokortin | - | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Sermorelin | GHRH analog | 50-300 mcg | 5 mg | 2 ml | Na zalogi | Izračunaj |
| Tesamorelin | GHRH analog | 1-2 mg | 10 / 20 mg | 2 ml | Na zalogi | Izračunaj |
| Thymosin Alpha-1 | Timusni peptid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Na zalogi | Izračunaj |
| Epithalon | Dolgoživost | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Na zalogi | Izračunaj |
| KPV | Imunski sistem / pregrada | 100-1000 mcg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Semax | Kognitivno | 100-1000 mcg | 10 / 30 mg | 2 ml | Na zalogi | Izračunaj |
| DSIP | Spanje | 50-500 mcg | 10 mg | 2 ml | Na zalogi | Izračunaj |
| 5-Amino-1MQ | Presnovno | 2,5-10 mg | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Pinealon | Raziskovalni peptid | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Survodutide | GLP-1/glukagon | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| NAD+ | Dolgoživost / kofaktor | 100-500 mg | 1000 mg | 10 ml | Na zalogi | Izračunaj |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| AOD-9604 | Izguba maščobe | 250-500 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH Fragment 176-191 | Presnovni fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| N-Acetyl Semax | Kognitivno | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH 191AA | Rastni hormon | 1-5 mg | 10 mg | 1 ml | Samo kalkulator | Izračunaj |
Vrednosti so za orientacijo v raziskovalnem kontekstu in ne nadomeščajo strokovnega nasveta.
Običajne začetne vrednosti za orientacijo. Vsaka vrstica odpre kalkulator za ta peptid.
| Peptid | Kategorija | Običajen odmerek | Velikosti stekleničk | BAC (začetek) | Na voljo | Izračun |
|---|---|---|---|---|---|---|
| VIP | Raziskovanje nevropeptidov | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Retatrutide | GLP-1/GIP/GCG | 0,5-12 mg | 2 / 5 / 10 / 15 mg | 2 ml | Na zalogi | Izračunaj |
| Cagrilintide | Analog amilina | - | 5 mg | 2 ml | Na zalogi | Izračunaj |
| Tirzepatide | GLP-1/GIP | 2,5-15 mg | 10 / 15 / 20 / 30 / 60 / 90 mg | 2 ml | Na zalogi | Izračunaj |
| GHK-Cu | Bakrov peptid | 1-4 mg | 10 / 20 / 50 mg | 5 ml | Na zalogi | Izračunaj |
| AHK-Cu | Bakrov peptid | - | 100 mg | 5 ml | Na zalogi | Izračunaj |
| BPC-157 | Obnova tkiva | 0,2-0,5 mg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| TB-500 | Thymosin Beta-4 | 2-5 mg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| CJC-1295 (brez DAC) | GHRH analog | 100-200 mcg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Ipamorelin | GHRP | 200-300 mcg | 2 / 5 mg | 2 ml | Na zalogi | Izračunaj |
| PT-141 | Bremelanotide | - | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| MOTS-c | Mitohondrijski | 5-10 mg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Selank | Anksiolitik | 150-500 mcg | 2 / 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| SS-31 | Elamipretide | 0,1-1 mg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Glow Stack | Stack | 0,5-2 mg | 70 mg | 3 ml | Na zalogi | Izračunaj |
| Klow Stack | Stack | 0,5-2 mg | 55 mg | 3 ml | Na zalogi | Izračunaj |
| Melanotan II | Melanokortin | 100-1000 mcg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Melanotan I | Melanokortin | - | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Sermorelin | GHRH analog | 50-300 mcg | 5 mg | 2 ml | Na zalogi | Izračunaj |
| Tesamorelin | GHRH analog | 1-2 mg | 10 / 20 mg | 2 ml | Na zalogi | Izračunaj |
| Thymosin Alpha-1 | Timusni peptid | 0,8-3,2 mg | 1.6 / 5 / 10 mg | 1 ml | Na zalogi | Izračunaj |
| Epithalon | Dolgoživost | 2-10 mg | 10 / 20 / 50 mg | 2 ml | Na zalogi | Izračunaj |
| KPV | Imunski sistem / pregrada | 100-1000 mcg | 5 / 10 mg | 2 ml | Na zalogi | Izračunaj |
| Semax | Kognitivno | 100-1000 mcg | 10 / 30 mg | 2 ml | Na zalogi | Izračunaj |
| DSIP | Spanje | 50-500 mcg | 10 mg | 2 ml | Na zalogi | Izračunaj |
| 5-Amino-1MQ | Presnovno | 2,5-10 mg | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Pinealon | Raziskovalni peptid | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Survodutide | GLP-1/glukagon | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| Kisspeptin-10 | KISS1R / GPR54 | - | 10 mg | 2 ml | Na zalogi | Izračunaj |
| NAD+ | Dolgoživost / kofaktor | 100-500 mg | 1000 mg | 10 ml | Na zalogi | Izračunaj |
| Semaglutide | GLP-1 | 0,25-2,4 mg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| AOD-9604 | Izguba maščobe | 250-500 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH Fragment 176-191 | Presnovni fragment | 100-500 mcg | 2 / 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| N-Acetyl Semax | Kognitivno | 100-1000 mcg | 5 / 10 mg | 2 ml | Samo kalkulator | Izračunaj |
| Hexarelin | GHRP | 50-200 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-6 | GHRP | 50-300 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| GHRP-2 | GHRP | 50-250 mcg | 2 / 5 mg | 2 ml | Samo kalkulator | Izračunaj |
| HGH 191AA | Rastni hormon | 1-5 mg | 10 mg | 1 ml | Samo kalkulator | Izračunaj |
Vrednosti so za orientacijo v raziskovalnem kontekstu in ne nadomeščajo strokovnega nasveta.
Izberite peptid in odprla se bo njegova stran kalkulatorja z že izpolnjenimi vrednostmi.
Izberite peptid in odprla se bo njegova stran kalkulatorja z že izpolnjenimi vrednostmi.